저희 연구실은 생물과 관련하여 나노구조체를 연구하는 연구실입니다.
주요 분야는 NATURE-INSPIRED DESIGN OF MATERIALS, NUCLEIC ACID NANOTECHNOLOGY, Nanomaterials for Energy Conversion and Storage, DESIGN AND SYNTHESIS OF FUNCTIONAL POLYMERS, NANO/MICRO FABRICATION, IN VIVO BIOIMAGING AND THERAPEUTICS 입니다.

 

Nano-Bio Interface Laboratory

(Korea Advanced Institute of Science and Technology)

 

NATURE-INSPIRED DESIGN OF MATERIALS
- Biomimetic Synthesis of Inorganic and Organic-inorganic Hybrid Materials
- Advanced Phage Display for Self-assembly of Molecules and Materials

NUCLEIC ACID NANOTECHNOLOGY
- DNA Origami for Exciton Control
- Small Interfering RNA (siRNA) Nanostructures

Nanomaterials for Energy Conversion and Storage
- Photocatalytic Water Splitting for Hydrogen Evolution

DESIGN AND SYNTHESIS OF FUNCTIONAL POLYMERS
- Reactive Oxygen Species (ROS) Sensitive Degradable Polymers
- Biomimetic Functional Block Copolymers

NANO/MICRO FABRICATION
- Microfluidics for Emulsion Fabrication and Biological Applications
- Biomineralization Using Electrospun Polymer Nanofibers

IN VIVO BIOIMAGING AND THERAPEUTICS
- Identification and Applications of Tumor-specific Aptamers
- Cancer Theranostics for Personalized Medication

 

 

 

 

 

Nanostructures for Plasmonic Photochemistry

We design 3D-assembled plasmonic structures of nanoparticles, nanowire/rods, and thin films to effectively utilize the LSPR-induced hot carriers for relevant photochemical reactions.

 

Porous Inorganic-Polymer Hybrid Colloids

We utilize open porous polymer microspheres as a colloidal soft template for the immobilization of functional inorganic nanomaterials for practical applications in catalysis, biosensing, and cosmetics.

 

Surface Chemistry of Quantum Dots

We synthesize near-infrared copper-indium-sulfide (CIS) quantum dots and encapsulate them within protein nanoparticles for in vivo bio-imaging applications. We also synthesize water-dispersible DNA-modified quantum dots for bio-sensing applications.

 

DNA Scaffolds for Excited Energy Transfer

We employ DNA nanostructures as scaffolds for programmable assembly of chromophores, quantum dots, and plasmonic nanoparticles with high precision periodicity and stability to control exciton migration.

 

Cell-based Biosensors

We construct a complex of sensory cells that interact with neuronal cells upon external stimuli. The sensory-cell-to-neuronal-cell interactions are translated to signals that can be measured using a microelectrode chip.

 

Tumor-targeted Photodynamic Chemotherapy

The therapeutic efficacy of nanocarriers are limited by biological barriers, one of which includes the high intratumoral pressure caused by the complicated structure of the tumor microenvironment and aggressive nature of cancer cellular growth that impedes the extravasation of the nanocarriers and uniform distribution at the solid tumor. Given this problem, we are developing reactive oxygen species (ROS)-sensitive polymeric micelles that can release encapsulated chemotherapeutics photodynamically.

 

Tumor-targeted Nanocarriers

We are working on improving the target efficiency of drug delivery systems by increasing the tumor-targeting ligand multivalency of drug-loaded polymeric nanoparticles.

 

Fibrin-targeted Peptide Ligands

We are working on the identification of a novel peptide ligand targeting specific sites of fibrin using phage library.

 

 

Son H.Y., Ryu J.J., Lee H., Nam Y.S.
Silver-polydopamine Hybrid Coatings of Electrospun Poly(vinylalcohol) Nanofibers
Macromolecular Materials & Engineering, 2012 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Lee J.Y., LeeS.H., Oh M.H., Kim J.S., Park T.G., Nam Y.S
Prolonged Gene Silencing by siRNA/chitosan-g-deoxycholic acid Polyplexes Loaded within Biodegradable Polymer Nanoparticles
J. Controlled Release, 2012 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Kim J.S., Kim T.G., Kong W.H., Park T.G., Nam Y.S.
Thermally Controlled Wettability of Nanoporous Membrane Grafted with Catechol-tethered Poly(N-isopropylacrylamide)
Chem. Comm., 2012 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Lee Y., Kim J., Yun D.S., Nam Y.S., Shao-Horn Y., Belcher A.M.
Virus-templated Au and Au–Pt Core–shell Nanowires and Their Electrocatalytic Activities for Fuel Cell Applications
Energy Environ. Sci, 2012 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Reductively Dissociable siRNA-Polymer Hybrid Nanogels for Efficient Targeted Gene Silencing
Hong C.A., Kim J.S., Lee S.H., Kong W.H., Park T.G., Mok H., Nam Y.S
Adv. Func. Mater , 2012 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Dong Jae Lee, Hyun Su Park, Kunmo Koo, Jeong Yong Lee, Yoon Sung Nam, Wonhee Lee, and Moon Young Yang
Gold Binding Peptide Identified from Microfluidic Biopanning: An Experimental and Molecular Dynamics Study
Langmuir, 2019 , ,Vol. 35No. 2 ,pp. 522 ~ 528(SCIE, 0:0.0

Geok Leng Seah, Jeong Heon Yu, Bon Il Koo, Dong Jae Lee, and Yoon Sung Nam
Cancer-targeted Reactive Oxygen Species-degradable Polymer Nanoparticles for Near Infrared Light-induced Drug Release
Journal of Materials Chemistry B, 2018 , ,Vol. 0No. 6 ,pp. 7737 ~ 7749(SCIE, 0:0.0

Junsu Yun, Ann-Na Cho, Seung-Woo Cho, and Yoon Sung Nam
DNA-mediated Self-assembly of Taste Cells and Neurons for Taste Signal Transmission
Biomaterials Science, 2018 , ,Vol. 0No. 6 ,pp. 3388 ~ 3396(SCIE, 0:0.0

Jeong Yu Lee, Ho Yeon Son, Jae Chul Park, Jongnam Park, and Yoon Sung Nam
Paclitaxel-induced Formation of 3D Nanocrystal Superlattices within Injectable Protein-based Hybrid Nanoparticles
Chemical Communications, 2018 , ,Vol. 0No. 54 ,pp. 11586 ~ 11589(SCIE, 0:0.0

Yi Li, Tae Won Nam, Aliaksandra Rakovich, Riccardo Sapienza, Yeon Sik Jung, Yoon Sung Nam
Template Dissolution Interfacial Patterning of Single Colloids for Nanoelectrochemistry and Nanosensing, Joong Bum Lee, Harriet Walker
ACS Nano, 2021 , ,Vol. 0No. 0 ,pp. 0 ~ 0(SCIE, 0:0.0

Light-Activated Polydopamine Coatings for Efficient Metal Recovery from Electronic Waste
Kyeong Rak Kim, Jeonga Kim, Jin Woong Kim, Cafer T. Yavuz, Moon Young Yang*, and Yoon Sung Nam
Separation and Purification Technology, 2021 , ,Vol. 254No. 117674 ,pp. 0 ~ 0(SCIE, 0:0.0

Doyeon Kim, Sungho Lee, Daehwan Park, Yeong Sik Cho, Sunyoung Choi, Yoon Sung Nam*, Jin Woong Kim
Fabrication of Attractive Hectorite Nanoplatelets by High-pressure Homogenization for Shear-responsive Reversible Rheology Modification of Organogels
Journal of Industrial and Engineering Chemistry, 2020 , ,Vol. 90No. 0 ,pp. 274 ~ 280(SCIE, 0:0.0