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포항공과대학교 면역멤스 세포동역학 실험실
.JPG)
| 지도교수 | 도준상 |
|---|---|
| 전공분류 | 생체역학(Biomechanics), |
| 주소 | 경상북도 포항시 남구 효자동 산31번지 포항공과대학교 기계공학과 790-784 |
| 전화 | 054)279-5555 |
| 홈페이지 | http://imems.postech.ac.kr/ |
실험실소개
본 실험실은 다학제적인 (multidisciplinary) 연구방법으로 면역현상을 규명하고 면역시스템을 이용한 진단 및 치료방법을 개발하는 연구를 수행하고 있습니다.
복잡하고 역동적인 세포들간의 상호작용으로 구성되는 면역 시스템을 이해하고 통제하는데 있어서 기존의 생물학적인 방법은 많은 제약을 가지고 있습니다. 이러한 제약을 극복할 수 있는 대안으로써 본 실험실은 바이오멤스 (BioMicroElectroMechanical Systems) 기술 및 다양한 종류의 최첨단 영상기법을 활용하고 있습니다.
이러한 노력의 궁극적인 목적은 다양한 면역관련 질병의 예방/진단/치료기술의 향상을 통한 인류의 건강 증진에 있습니다.
연구분야
<Stydying immune system using BioMEMS and dynamic imaging>
Bio-friendly photoresist
Lymphocyte biology
Cancer immunotherapy
연구성과
C.A. Sabatos*, J. Doh*, S. Chakravarti, P.G. Pandurangi, R.S. Friedman, A.J. Tooley and M.F. Krummel
A Synaptic Basis for Paracrine Interleukin-2 Signaling in Activating T cells.
Immunity, 2008, Vol. 0, No. 0, pp. 0~ 0
P.J. Yoo, N.S. Zacharia, J. Doh, K.T.Nam, A.M. Belcher, and P.T. Hammond
Controlling Surface Mobility in Interdiffusing Polyelectrolyte Multilayers
ACS Nano , 2008, Vol. 2, No. 3, pp. 0~ 0
J. Doh and D.J. Irvine
Immunological synapse arrays: Patterned protein surfaces that modulate immunological synapse structure formation in T cells
Proc. Natl. Acad. Sci. USA , 2006, Vol. 103, No. 15, pp. 0~ 0
J.S. Katz, J. Doh, and D.J. Irvine
Composition-Tunable Properties of Amphiphilic Comb Copolymers Containing Protected Methacrylic Acid Groups for Multicomponent Protein Patterning
Langmuir, 2006, Vol. 22, No. 1, pp. 0~ 0
J. Doh*, M. Kim and M.F Krummel
Cell-Ladem Microwells For The Study Of Multicellularity In Lymphocyte Fate Decisions
Biomaterials , , Vol. 0, No. 0, pp. 0~ 0
Junsang Doh, Daniel Fletcher, Matthiey Piel
Microfluidics in Cell Biology Part A: Microfluidics for Multicellular Systems
Methods in Cell Biology, 2018, Vol. 0, No. 0, pp. 1461~ 0
J. Lee, H.K. Huh, S. Park, S.J. Lee, and J. Doh
Endothelial cell monolayer-based microfluidic systems mimicking complex in vivo microenvironments for in vitro assessment of leukocyte dynamics in inflamed blood vessels
Method Cell Biol, 2018, Vol. 0, No. 0, pp. 0~ 0
H.M. Kim, H. Park, and J. Doh
Multifunctional microwell arrays for single cell level functional analysis of lymphocytes
Bioconjug. Chem, 2018, Vol. 0, No. 0, pp. 0~ 0
S.M. Park, H.M. Kim, K.H. Song, S. Eom, H. Park, J. Doh and D.S. Kim
Ultra-thin, aligned, free-standing nanofiber membranes to recapitulate multi-layered blood vessel/tissue interface for leukocyte infiltration studies
Biomaterials, 2018, Vol. 0, No. 0, pp. 0~ 0
A Synaptic Basis for Paracrine Interleukin-2 Signaling in Activating T cells.
Immunity, 2008, Vol. 0, No. 0, pp. 0~ 0
P.J. Yoo, N.S. Zacharia, J. Doh, K.T.Nam, A.M. Belcher, and P.T. Hammond
Controlling Surface Mobility in Interdiffusing Polyelectrolyte Multilayers
ACS Nano , 2008, Vol. 2, No. 3, pp. 0~ 0
J. Doh and D.J. Irvine
Immunological synapse arrays: Patterned protein surfaces that modulate immunological synapse structure formation in T cells
Proc. Natl. Acad. Sci. USA , 2006, Vol. 103, No. 15, pp. 0~ 0
J.S. Katz, J. Doh, and D.J. Irvine
Composition-Tunable Properties of Amphiphilic Comb Copolymers Containing Protected Methacrylic Acid Groups for Multicomponent Protein Patterning
Langmuir, 2006, Vol. 22, No. 1, pp. 0~ 0
J. Doh*, M. Kim and M.F Krummel
Cell-Ladem Microwells For The Study Of Multicellularity In Lymphocyte Fate Decisions
Biomaterials , , Vol. 0, No. 0, pp. 0~ 0
Junsang Doh, Daniel Fletcher, Matthiey Piel
Microfluidics in Cell Biology Part A: Microfluidics for Multicellular Systems
Methods in Cell Biology, 2018, Vol. 0, No. 0, pp. 1461~ 0
J. Lee, H.K. Huh, S. Park, S.J. Lee, and J. Doh
Endothelial cell monolayer-based microfluidic systems mimicking complex in vivo microenvironments for in vitro assessment of leukocyte dynamics in inflamed blood vessels
Method Cell Biol, 2018, Vol. 0, No. 0, pp. 0~ 0
H.M. Kim, H. Park, and J. Doh
Multifunctional microwell arrays for single cell level functional analysis of lymphocytes
Bioconjug. Chem, 2018, Vol. 0, No. 0, pp. 0~ 0
S.M. Park, H.M. Kim, K.H. Song, S. Eom, H. Park, J. Doh and D.S. Kim
Ultra-thin, aligned, free-standing nanofiber membranes to recapitulate multi-layered blood vessel/tissue interface for leukocyte infiltration studies
Biomaterials, 2018, Vol. 0, No. 0, pp. 0~ 0
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